We believe that the current list of Pharmacy Only Non-Prescription Medicines should be analysed and reviewed, and reflection is needed on widening the medicines included in this category (by reclassifying certain Prescription Medicines into Pharmacy Only Non-Prescription Medicines and Non-Prescription Medicines (NPM) into Pharmacy Only Non-Prescription Medicines). This list is intended to be a pharmaceutical intervention tool that aims to increase access to medicines and, simultaneously, guarantee these therapies’ safety and rational use, generating evidence on their use. In this way, it will be possible to increase the number of therapies dispensed in pharmacies without a prescription, integrated into protocols approved by INFARMED, I.P., with data collection and processing to be made available to the health authorities.